Harvard University bought the device developed by Turkish engineers

gave | Saturday, July 10, 2021 – 17:35 | Last Updated: 10 07 2021 – 17:35

According to the breaking news; A special headset developed by Turkish engineers, used in the treatment of stress-related diseases by electrically stimulating the vagus nerve in the ear, was purchased by Harvard University. The device will be used by doctors and researchers at Harvard Medical School to conduct research in the field of infection.

Special earphones developed by Turkish engineers prevent the occurrence of stress-related diseases by electrically stimulating the vagus nerve in the ear. The device called Vagustim, which can be controlled with a mobile application, will be used in the treatment of chronic pain such as migraine and fibromyalgia, sleep disorders, functional intestinal system disorders, depression and obesity.

Bahçeşehir University Faculty of Health Sciences Department of Physiotherapy, who is part of the team that developed the device, Dr. Instructor Ali Veysel Özden, its member, said, “Harvard liked this device and bought 5 of them. It will be used by doctors and researchers at Harvard Medical School for research in the field of infection. Our goal is to document the device. Once we get FDA approval, it can easily be used in human studies and other diseases. will open,” he said.


Explaining that the vagus nerve is an important part of the autonomic nervous system, Dr. Özden said, “The nerve that provides the body to calm and relax and provides the right digestion. It comes out of the brain stem and reaches almost all internal organs and makes them work. Stress is one of the most important problems of our age. In case of stress, the vagus nerve is suppressed. The most important reason for the emergence of stress-related disorders is the suppression of the vagus nerve. Migraine It is a very important disease and it has a lot to do with stress. We can count all chronic pain, except migraine, among these diseases. Sleep disorders are among these diseases. Apart from that, we can count functional intestinal system disorders. Depression is among the diseases associated with stress. Obesity is one of the problems of our age. One of the causes of obesity “One of them is that stress suppresses the feeling of hunger and causes overeating after inhibiting it. Therefore, vagus nerve stimulation is used in many stress-related diseases.”


Explaining that the use of vagus nerve stimulation in the treatment of epilepsy began in 1997, Dr. Özden reminded that there are studies showing that the inflammation seen with the coronavirus and the vagus nerve can be stimulated in cases where there is an excessive inflammatory condition in the body, and said: “As we saw that the device can be effective in the area of ​​inflammation with the coronavirus, we made a correct positioning here. We developed the headset that can touch the point, we applied for a patent. Afterwards, we started the use of the headset in patients with its certification. We did clinical studies on this. Then we realized that the autonomic nervous system is very variable. Your nervous system can change a lot even during the day. We realized that you need a treatment method, that is, personalized treatment management. We have created a form in which personal data that can be controlled from the mobile phone are collected and the current can be adjusted individually. As soon as it got this form, it became the first device in the world. Yur Sales of the device abroad have started, but it is currently used in clinical trials.”


Stating that the warning goes to the brain, not directly to the organs, Dr. Özden said, “In this sense, it is a situation that increases reliability. Neck stimulation can be performed unilaterally, but ear stimulation can be performed bilaterally. Since it touches both points on the ear, this allows us to reduce the daily stimulation time. Our clinical experience so far has shown that 20-30 minutes of daily stimulation may be sufficient. It is not a one-time application. It is recommended to use it regularly for 2 months in order to increase the vagus activity to a sufficient level. We have a case report on a migraine patient. The pain level decreased by 90 percent in a patient for whom no treatment helped. We also have a publication about this. By neurologists publication,” he said.


Vagustim was entitled to receive a grant of approximately 1 million TL from 1511, one of TÜBİTAK’s most prestigious support programs, in 2020. Vagustim was cited as one of the 5 most promising initiatives among 188 Neurotechnology initiatives analyzed worldwide. The venture, which is preparing to complete a new investment round at the end of 2021, plans to grow by making faster progress in certification, mass production and marketing.